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Cancer Center



Oncology Clinical Trials

Oncology Clinical Trials

New hope in the fight against cancer


Thanks to a history of clinical trials research, people with cancer are living longer and with a better quality of life than ever before. Cancer research is advancing at a fast pace and, as a result, researchers are able to develop targeted therapies that are changing the standards of care and saving lives.
 

Some patients may fear that enrollment in a clinical trial means they may receive no treatment at all. The reality is that patients in studies receive either the best treatment currently known for their specific cancer, or a new, and possibly more effective, therapy. Placebos are never used in place of treatment when an existing therapy exists.
 

Lancaster General Health Cancer Center participates in numerous studies sponsored by the National Cancer Institute through groups such as the Eastern Cooperative Oncology Group, the Radiation Therapy Oncology Group and the American College of Surgeons Oncology Group.


Lancaster General Health is a member of the University of Penn Cancer Network.
 

Current oncology treatment trials open for participation:


Site Sponsor Study Title
Breast
B-43 NSABP A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
CREP UPCC Familial Breast Cancer Studies
3108 ECOG A Phase II Prospective Trial Correlating Progression Free Survival with CYP2D6 Activity in Patients with Metastatic Breast Cancer Treated with Single Agent Tamoxifen
2108 ECOG

A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer

MA-32 NCIC CTG Phase III Randomized Trial of the Effect of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
1007 SWOG A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less (RxPONDER: Rx for Positive Node, Endocrine Responsive Breast Cancer)
80702 WFU Impact of Genomics and exposures on disparities in breast cancer radiosensitivity
GI
80702 CALGB A Phase III Trial of 6 versus 12 treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer.
GU
0534 RTOG A Phase III Trial Of Short Term Androgen Deprivation With Pelvic Lymph Node Or Prostate Bed Only Radiotherapy (SPORT) In Prostate Cancer Patients With A Rising PSA After Radical Prostatectomy
0931 SWOG EVEREST: Everolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study
GYN
0249 GOG A Phase III Trial of Pelvic Radiation Therapy versus Vaginal Cuff Brachytherapy Followed by Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk Early Stage Endometrial Carcinoma
HEME
Simplicity Bristol -Myers Studying Interventions for Managing Patients with Chronic Myeloid Leukemia in Chronic Phase: The 5-Year Prospective Cohort Study
Lung

5508

ECOG Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC.

6508

ECOG A Phase II Study of L-BLP25 and Bevacizumab in Unresectable Stage IIIA and IIIB Non Squamous Non Small Cell Lung Cancer After Definitive Chemoradiation

G300504

GTx, Inc. Phase III, Randomized, Double-Blind, Placebo-Controlled Study of the Effect of GTx-024 on Muscle Wasting in Patients with Non-Small Cell Lung Cancer on First Line Platinum Plus a Taxane Chemotherapy

G300505

GTx, Inc.

Phase III, Randomized, Double-Blind, Placebo-Controlled Study of the Effect of GTx-024 on Muscle Wasting in Patients with Non-Small Cell Lung Cancer on First Line Platinum Plus a Non-Taxane Chemotherapy

 Updated 4-20-2012.



 
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